Effect of adriamycin on proliferation and apoptosis of connective tissue sheath cells of pig hair follicle in vitro 阿霉素对体外培养的猪毛囊真皮鞘细胞增殖和凋亡的影响
Hair-bulb looked like pellet, hair-papilla was evident, the bourn of internal root sheath and external root sheath was clear, the fiber of connective tissue sheath cell arrayed regularly. 毛球呈圆球形,毛乳头明显,内根鞘、外根鞘界限清楚,结缔组织性鞘细胞纤维规则排列。
【 Result 】 The hair follicle structure of cashmere goat was in the same manner compared with other animals, which was composed of hair bulb, connective tissue sheath, outer root sheath, inner root sheath and hair shaft. 【结果】绒山羊的毛囊结构同其它动物一样,由毛球、连接组织鞘、外根鞘、内根鞘和毛干几部分组成。
The bourn of internal root sheath and external root sheath was blurry, the fiber of connective tissue sheath cell arrayed disordered, the number of connective tissue cell reduced. 内根鞘、外根鞘界限模糊,结缔组织性鞘细胞纤维排列杂乱,结缔组织细胞减少。
The apoptosis rate of connective tissue sheath cells after the treatment with varied concentrations of adriamycin for 24 h was detected by flow cytometry. 用流式细胞仪检测不同剂量的阿霉素作用24h后猪毛囊真皮鞘细胞的凋亡率。
Structure of hair follicle is complex, containing at least seven types of cells including epithelial components ( hair matrix cell and outer root sheath) and mesenchymal components ( follicular papilla and connective tissue sheath). 毛囊结构复杂,含有上皮成分(毛母质和外根鞘)和真皮成分(真皮乳头和结缔组织鞘)的至少七种细胞。